What are the principles of combination therapy?
Joint drug use primarily refers to the treatment using two or more drugs, with the aim of curing diseases. Understanding the principles of medication during treatment is crucial to avoid toxic and adverse effects, as well as prevent opposite outcomes after treatment. It is important to understand the interactions between drugs, and medication should be administered with caution to avoid adverse reactions and consequences.
1.
Joint drug use refers to the simultaneous or sequential application of two or more drugs to achieve therapeutic goals. The primary outcomes are to increase the efficacy of drugs or reduce their toxic and adverse effects, though opposite results may also occur sometimes. Therefore, rational joint drug use should be based on the principle of enhancing efficacy and/or reducing adverse reactions. Drug interactions during joint drug use include those affecting pharmacokinetics and pharmacodynamics. Additionally, the use of too many drug varieties increases the incidence of drug interactions, affecting drug efficacy or toxicity. Therefore, when administering drugs to patients, caution should be exercised to minimize the number of drug types and reduce adverse drug reactions caused by drug interactions.
2.
Joint drug use refers to the simultaneous or sequential application of two or more drugs to achieve therapeutic goals. The primary outcomes are to increase the efficacy of drugs or reduce their toxic and adverse effects, though opposite results may also occur sometimes.
