What are the effects of sulfamethoxazole?
The primary function of sulfamethoxazole is to resist infections, exhibiting effective therapeutic effects on various pathogens such as Enterobacteriaceae, Escherichia coli, Haemophilus influenzae, etc. It has a good anti-inflammatory effect and is often used to treat urinary tract infections, otitis media, adult chronic bronchitis, and so on. Medication should be taken according to doctor's advice, and relevant contraindications should be understood.
1. Functions of Sulfamethoxazole:
⑴ Urinary tract infections caused by sensitive strains of Klebsiella, Escherichia coli, Enterobacteriaceae, Proteus vulgaris, Proteus mirabilis, and Morganella.
⑵ Acute otitis media in children over 2 years old caused by Haemophilus influenzae and Streptococcus pneumoniae.
⑶ Acute exacerbations of adult chronic bronchitis caused by Haemophilus influenzae and Streptococcus pneumoniae.
⑷ Intestinal infections and Shigella infections caused by sensitive strains of Shigella flexneri or Shigella sonnei.
⑸ As the preferred treatment for Pneumocystis carinii pneumonia.
⑹ Prevention of Pneumocystis carinii pneumonia, suitable for patients with a history of at least one episode of Pneumocystis carinii pneumonia or HIV-infected adults with CD4 lymphocyte counts ≤ 200/mm3 or less than 20% of the total lymphocyte count.
⑺ Traveler's diarrhea caused by enterotoxigenic Escherichia coli (ETEC).
2. Contraindications of Sulfamethoxazole:
⑴ Prohibited for those allergic to SMZ and TMP.
⑵ Prohibited for patients with megaloblastic anemia as it blocks folate metabolism, aggravating folate deficiency in these patients.
⑶ Prohibited for infants less than 2 months old.
⑷ Prohibited for those with severe liver and kidney dysfunction.
