What are the Effects of Ondansetron?

Ondansetron is used for antiemetic purposes, with excellent effects on nausea and vomiting caused by chemotherapy, radiotherapy, and postoperative conditions. However, it can cause liver damage, affect the digestive and nervous systems, leading to symptoms such as dry stool, abdominal distension, headache, dizziness, tachycardia, and chest discomfort. Some patients may also experience an increase in aminotransferase levels. Therefore, it is crucial to use ondansetron cautiously and strictly control the dosage.

What are the effects of ondansetron?

1. Ondansetron is a 5-HT3 receptor antagonist with antiemetic properties.
2. It is primarily used clinically for nausea and vomiting caused by cytotoxic chemotherapy and radiotherapy.
3. It can also be used for the prevention and treatment of postoperative nausea and vomiting, with excellent results.

What are the side effects of ondansetron?

1. Liver damage: Ondansetron is metabolized by the liver, which can lead to liver dysfunction.
2. Dry stool and abdominal distension: These symptoms are caused by ondansetron's inhibition of intestinal motility.
3. Rash: Skin reactions such as erythema, maculopapular rash, or transient erythema may occur around the injection site.
4. Headache, dizziness, tachycardia, and chest discomfort.
5. Transient asymptomatic elevations in aminotransferase levels may occur in some patients.
6. Other rare side effects include akathisia, bronchospasm, diarrhea, epileptic seizures, and hypokalemia.