What Are the Benefits of Wu Tou Herb?

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Aconitum Herb: Its Efficacy and Toxicity

Aconitum herb possesses analgesic and local anesthetic effects, making it a commonly used traditional Chinese medicinal herb. However, it is crucial to be aware of its toxicity when administering it to avoid adverse reactions such as intoxication, palpitations, and arrhythmia due to improper usage. External application is a common method, but it is essential to avoid excessive use.

1. Efficacy of Aconitum Herb

Analgesic Effect: Aconitum herb exhibits significant analgesic properties. Its analgesic potency at dosages of 0.19, 0.095, and 0.048g/kg exceeds that of morphine at dosages of 12, 6, and 3mg/kg, respectively. However, these dosages can cause toxic reactions, and the therapeutic index of aconitum (3.91) is significantly lower than that of morphine (48.58). Experiments using the hot plate method in mice have demonstrated analgesic effects of both beiwualkaloid and hypaconitine.

Local Anesthetic Effect: Beiwualkaloid exhibits local anesthetic properties in animals.

2. Toxicity of Aconitum Herb

The toxicity of aconitum herb is extremely potent to humans. Typically, ingestion of only 3 to 4 milligrams can cause palpitations, arrhythmia, and even cardiac arrest. Raw aconitum herb is highly toxic and is primarily used externally, such as for application, washing, and soaking. When using processed aconitum herb, it should be decocted first, and the dosage should be carefully controlled, typically ranging from 3 to 6 grams. Prolonged decoction of aconitum herb can reduce its toxicity.