What are the key differences between Cefuroxime Axetil and Cefixime?

The main difference between Cefuroxime Axetil Tablets and Cefixime lies in the fact that Cefixime has a stronger antibacterial effect than Cefuroxime Axetil Tablets. Both drugs are common antibacterial agents that can effectively treat some bacterial infections. Cefuroxime Axetil is generally used to treat otolaryngological infections, uncomplicated urinary tract infections, and other diseases. Here are the details:

1. Cefuroxime Axetil Tablets have good antibacterial effects, effectively inhibiting Streptococcus pyogenes, Streptococcus pneumoniae, Staphylococcus, methicillin-sensitive strains, Moraxella catarrhalis, Neisseria gonorrhoeae, Haemophilus influenzae, etc. It also exhibits good antibacterial effects against Escherichia coli, Klebsiella, Proteus, but Pseudomonas aeruginosa and other Pseudomonas species, Acinetobacter species, and Enterococcus species are resistant to Cefuroxime Axetil Tablets.

2. Cefixime has antibacterial effects on some Gram-positive and Gram-negative bacteria, especially Streptococcus (except Enterococcus), Streptococcus pneumoniae, Neisseria gonorrhoeae, Branhamella catarrhalis, Escherichia coli, Klebsiella, Serratia, Proteus, Haemophilus influenzae, etc. Cefixime granules are very stable against β-lactamases produced by various bacteria and show excellent antibacterial activity against β-lactamase-producing bacteria.