Introduction to Fluconazole Capsules

There are various types of diseases caused by bacterial infections, and antimicrobial agents are required for the treatment of such diseases. Fluconazole capsules can be used to treat diseases caused by Candida, Cryptococcus, and Coccidioides, such as peritonitis, pneumonia, and urinary tract infections. Since many people may be using Fluconazole capsules for the first time and may not be fully aware of its usage, let's explore what it is, how to take it, and if there are any side effects.

What is Fluconazole Capsule?

Fluconazole capsule is used for the following purposes:

• Candidiasis: Treatment of oral and esophageal Candida infections; disseminated candidiasis, including peritonitis, pneumonia, and urinary tract infections; Candida vulvovaginitis. It can also be used to prevent Candida infections in patients undergoing bone marrow transplantation who are receiving cytotoxic drugs or radiation therapy.
• Cryptococcosis: Treatment of extrameningeal cryptococcal infections; when treating cryptococcal meningitis, this medication can be used as maintenance therapy after initial treatment with amphotericin B combined with fluorocytosine.
• Coccidioidomycosis
• Prophylactic treatment for patients receiving chemotherapy, radiotherapy, and immunosuppressive therapy.
• This medication can also be used as an alternative to itraconazole for the treatment of blastomycosis and histoplasmosis.

How to Take Fluconazole Capsules?

The dosage of this medication varies depending on the type of disease being treated:

• For disseminated candidiasis, the initial dose is 0.4 grams, followed by 0.2 grams once daily for a total of four weeks. After symptoms have improved, continue the medication for at least another two weeks.
• For esophageal Candida infections, the initial dose is 0.2 grams, followed by 0.1 grams once daily for three weeks.
• For oral Candida infections, the initial dose is 0.2 grams, followed by 0.1 grams once daily for at least two weeks.
• For Candida vulvovaginitis, a single dose of 0.15 milligrams is recommended.
• For prophylactic use in preventing Candida infections, the recommended dose is 0.2 to 0.4 grams once daily.

Side Effects of Fluconazole Capsules

Possible side effects of Fluconazole capsules include:

• Common gastrointestinal reactions such as nausea, vomiting, abdominal pain, or diarrhea.
• Allergic reactions manifesting as rash, occasionally severe exfoliative dermatitis (often accompanied by liver damage), and exudative erythema multiforme.
• Hepatotoxicity: Mild and transient elevations in serum aminotransferase levels may occur during treatment. Symptoms of liver toxicity may occasionally develop, especially in patients with severe underlying diseases (such as AIDS and cancer).
• Dizziness and headache may be observed.
• Certain patients, especially those with severe underlying diseases (such as AIDS and cancer), may experience abnormal renal function.
• Occasional transient changes in hematological parameters such as neutropenia and thrombocytopenia may occur, especially in patients with severe underlying diseases (such as AIDS and cancer).

Please consult a healthcare professional for more information and advice on the use of Fluconazole capsules.