Can long-term use of Omeprazole lead to stomach cancer?

Omeprazole is a commonly used drug for the treatment of gastric diseases. Its main function is to protect the gastric mucosa of patients from the harm of gastric acid and other substances. The general course of treatment for Omeprazole is relatively long, so some patients may worry about whether long-term use of Omeprazole will lead to gastric cancer. In fact, generally speaking, this situation does not occur. The toxic and side effects of Omeprazole itself are relatively small. Of course, it is necessary to follow the doctor's advice when using the drug.

Omeprazole capsules are effective drugs for the treatment of gastric ulcer and duodenal ulcer. These drugs themselves do not damage the gastrointestinal mucosa, but mainly cause indigestion due to overuse. Therefore, the continuous use of Omeprazole capsules for the treatment of gastric ulcer and duodenal ulcer should not exceed 1.5 to 2 months. If the condition has not improved by then, other anti-ulcer drugs can be prescribed by the doctor. In addition, if the symptoms of gastric ulcer and duodenal ulcer do not improve or new situations occur after a period of regular treatment, such as changes in pain rhythm or aggravation of symptoms, the possibility of gastric cancer should be vigilant.

Omeprazole is a proton pump inhibitor that inhibits gastric acid secretion by inhibiting H+/K+-ATPase. Its main function is to prevent the formation of gastric acid, and it is suitable for the treatment of gastric ulcer, duodenal ulcer, stress ulcer, reflux esophagitis, and gastrinoma. The course of treatment for digestive ulcers with Omeprazole is 4-8 weeks, and the course of treatment for reflux esophagitis is usually 8 weeks. Long-term use is generally not recommended, and it should be used under the guidance of a doctor according to the patient's condition. It is usually taken in the morning or twice a day, usually half an hour before meals.