What is the best antibiotic to use for typhoid fever?

There is no definitive statement on the best antibiotic for typhoid fever in clinical practice. Patients can use quinolones, cephalosporins, and other medications under the guidance of their physicians.

1. Quinolones:

This includes levofloxacin hydrochloride capsules and ciprofloxacin tablets. These drugs are characterized by a broad antibacterial spectrum and strong bactericidal power. They exhibit strong killing effects on various Gram-negative bacilli and Gram-positive cocci in vitro, with low toxicity and fewer adverse reactions. They are currently one of the most widely used third-generation quinolones in clinical practice.

2. Cephalosporins:

Primarily comprising amoxicillin sodium clavulanate potassium for injection and piperacillin sodium and tazobactam sodium for injection. These drugs belong to β-lactam antibiotics and exert their anti-infective effects by inhibiting the synthesis of bacterial cell walls. They are suitable for various severe infections caused by sensitive bacteria, such as sepsis, meningitis, pneumonia, and biliary system infections.

3. Other Types:

This includes a variety of antibiotics such as penicillins, macrolides, and aminoglycosides. However, the specific medication should be selected based on the patient's condition. It is recommended to administer these medications under the guidance of a professional physician or pharmacist. For patients with significant fever, non-steroidal anti-inflammatory drugs such as ibuprofen sustained-release capsules and diclofenac sodium sustained-release tablets can be prescribed for fever reduction. In case of diarrhea, oral montmorillonite powder can be administered for relief. Additionally, it is important to drink plenty of water to promote metabolism and facilitate recovery.