What is the significance of a creatinine level of 185?

A creatinine level of 185 μmol/L indicates an elevated level, often associated with conditions such as acromegaly and polycystic kidney disease.

1. Acromegaly: This generally refers to an endocrine and metabolic disorder caused by long-term excessive secretion of growth hormone, primarily due to pituitary growth hormone tumors or pituitary growth hormone cell hyperplasia. Patients may exhibit various systemic abnormalities such as frontal bone hyperplasia, skin thickening, and hypertension. With a creatinine level of 185 μmol/L, medications such as octreotide and lanreotide can be used for clinical treatment, and surgical treatment is also an option.

2. Polycystic Kidney Disease: This is a congenital genetic disorder with an unknown pathogenesis. It is currently believed to be possibly related to tubular obstruction or localized dilation in different parts of the nephron, mostly affecting both kidneys. In the early stages, only a few cysts may be present in the kidneys, but they later develop into cysts throughout the kidney, varying in size and compressing the renal parenchyma, reducing nephron count. With a creatinine level of 185 μmol/L, surgical treatment can be considered.