What Are the Indicators of Active Systemic Lupus Erythematosus?

Systemic lupus erythematosus (SLE) is a relatively common disease that belongs to autoimmune inflammatory connective tissue disease. It often occurs in young women. Early symptoms are relatively mild and atypical. If the condition is severe, patients may experience significant discomfort, often resulting in joint pain, swelling, oral ulcers, hair loss, and other symptoms. It is important for patients to promptly undergo relevant examinations at the hospital. So, what are the indicators of the active phase of SLE? Let's take a look.

What are the indicators of the active phase of SLE?

Patients should have corresponding symptoms of activity within the last 10 days, such as the appearance of new rashes, recurrent joint pain, swelling, hair loss, and oral ulcers. Blood tests may indicate decreased levels of three blood cell lines, further decreased complement levels, and increased levels of double-stranded DNA antibodies. Additionally, inflammatory markers such as erythrocyte sedimentation rate and C-reactive protein may be significantly elevated. There may also be hyperglobulinemia, positive rheumatoid factor, or blood tests indicating a significant increase in platelets. Based on these clinical manifestations and activity indicators, a comprehensive judgment can be made that the patient is currently in the active phase of SLE.

Precursors of Systemic Lupus Erythematosus

First, general fatigue. This is because the body is being attacked by foreign substances, resulting in feelings of exhaustion and weakness. Second, persistent high fever. This is a physiological response caused by the immune system fighting against viruses. Third, butterfly-shaped rash. This usually appears on the cheeks and is one of the most common early symptoms of SLE, affecting all patients with the disease. Some individuals may also experience other types of skin rashes.