What are the effects of mannitol injection?

Mannitol Injection can promote diuresis, dehydration, and reduce intracranial pressure. After entering the human body and being filtered by the glomerulus, Mannitol Injection can promote osmotic diuresis. It can increase the osmotic pressure of blood vessels, reduce water entering the blood vessels, and reduce tissue edema, thereby reducing intracranial pressure. However, the injection of mannitol can easily lead to imbalance of water and electrolytes in the body, so monitoring must be paid attention to. Here are the main applications:

1. For the treatment of cerebral edema caused by various reasons, to reduce intracranial pressure and prevent cerebral hernia.

2. To reduce intraocular pressure, which can effectively reduce intraocular pressure and is used for other ineffective methods to reduce intraocular pressure or as a preparation before intraocular surgery.

3. Osmotic diuretics are used to distinguish oliguria caused by pre-renal factors or acute renal failure, and can also be used to prevent acute tubular necrosis caused by various reasons.

4. As an auxiliary diuretic measure, it is used to treat nephrotic syndrome and ascites, especially when accompanied by hypoproteinemia.

5. When some drugs are overdosed or poisoned by toxic substances, mannitol can be used to promote the excretion of substances and prevent renal toxicity.

Mannitol may also have some side effects during use. Imbalance of water and electrolytes is a common side effect, so special attention should be paid to monitoring the balance of water and electrolytes during use. It may also cause symptoms of the central nervous system, difficulties in urination, and may have a certain impact on renal function. Therefore, special attention should also be paid when using it.