"What Indicators Are Abnormal in Leukemia?"

Leukemia patients typically exhibit abnormalities in the blood system and bone marrow examination. If you suspect that you have leukemia, it is recommended to promptly visit the hematology department of a hospital and complete relevant examinations under the guidance of a doctor.

1. Blood System:

In the peripheral blood of leukemia patients, blast cells may be present with a significantly increased absolute value, accompanied by a reduction in red blood cells and platelets. Additionally, infiltration of leukemia cells can lead to hepatosplenomegaly.

2. Bone Marrow Examination:

Bone marrow aspiration smear reveals the presence of ≥20% of primitive and blast cells, accompanied by a left shift of nuclei. Typically, the granulocytic, erythroid, and megakaryocytic lineages in the bone marrow are suppressed, although some patients may exhibit extreme hyperplasia or hypoplasia. Furthermore, if specific antibodies are detected during immunological examination, it suggests the possibility of acute promyelocytic leukemia. Chromosomal examination revealing genetic rearrangements such as t(9;22) indicates chronic myeloid leukemia. Flow cytometry can also be used to detect minimal residual disease to assess for recurrence.

After diagnosis, treatment may involve medications such as cyclophosphamide injection and methotrexate injection, administered under medical supervision. Additionally, allogenic hematopoietic stem cell transplantation may be considered as an option to improve the condition. In daily life, it is essential to strengthen nutritional supplementation and nursing care to avoid compromising one's health.