What are the Effects of Oxazepam?

The main function of Oxazepam tablets is to relieve anxiety, tension, and excitement within a short period of time. It can also be used for hypnotic purposes. If there are symptoms of anxiety as well as depression, Oxazepam tablets can be used as an adjuvant drug and can also help alleviate acute alcohol withdrawal symptoms. Additionally, Oxazepam tablets have a strong muscle relaxing effect, and it is essential to follow the doctor's instructions when taking the medication.

Oxazepam tablets are short-acting benzodiazepine sedative-hypnotic drugs. They are the active metabolites of diazepam, chlordiazepoxide, and demoxepam. They are well absorbed orally and reach peak blood concentrations within approximately three hours. They can cross the placental barrier and be secreted into breast milk. They have a high binding rate with plasma proteins and a half-life of 5-10 hours. They are inactivated by conjugation with glucuronic acid in the liver, and metabolites and a small amount of the original drug are excreted in the urine. Oxazepam tablets have similar effects to diazepam, with strong anti-anxiety and anti-convulsant effects, but weaker hypnotic effects. They are mainly used clinically for anxiety disorders and can also be used as adjunctive treatment for insomnia and epilepsy.

This medication acts on the benzodiazepine receptors (BZR) in the central nervous system, enhancing the binding of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) to GABAA receptors, thereby increasing the activity of the GABA system. BZR can be divided into type I and type II. It is believed that the excitation of type I receptors can explain the anti-anxiety effects of BZ drugs, while type II receptors are related to the sedative and muscle relaxant effects of these drugs. As the dosage increases, the clinical manifestations can range from mild sedation to hypnosis and even coma. Long-term use can lead to dependence.