What are the Benefits and Effects of Persantine?

Update Date: Source: Network

Introduction to Dipyridamole

Dipyridamole has the effect of preventing thrombosis, anticoagulation, expanding coronary arteries, and promoting circulation. It is mainly used in cardiovascular system diseases, such as the treatment of ischemic heart disease and stroke. It is a prescription drug that may cause side effects such as abdominal pain, diarrhea, nausea, and vomiting after use. It should be taken under the guidance of a doctor and should not be used without consulting a doctor.

What is Dipyridamole?

Dipyridamole, also known as Persantin, is a drug that dilates coronary arteries and prevents thrombus formation. It is mainly used for the treatment of ischemic heart disease and stroke, and is also used in the treatment of other diseases in small quantities. Its side effects may include headache, dizziness, nausea, vomiting, diarrhea, and other adverse reactions. When used with heparin, it can cause bleeding tendency, occasional rash, and coronary artery steal phenomenon. It was once a commonly used drug for the treatment of coronary heart disease, but now it is rarely used for anti-myocardial ischemia. Its anti-platelet aggregation effect can be used in heart surgery or valve replacement surgery to reduce the formation of thromboembolism.

Functions and Effects of Dipyridamole

1. Inhibit platelet aggregation and prevent thrombus formation.

2. Expand coronary arteries, increase coronary blood flow, improve myocardial ischemia, and prevent angina pectoris.

3. Enhance the anticoagulant effect of heparin and oral anticoagulants.

4. Used for secondary prevention after acute myocardial infarction.

5. Used for the prevention of thrombosis after artificial heart valve replacement and artificial blood vessel transplantation.

6. Inhibit virus proliferation and used for the treatment of viral upper respiratory tract infection and rotavirus enteritis.

Adverse Reactions of Dipyridamole

Adverse reactions of Dipyridamole include gastrointestinal reactions, headache, dizziness, fatigue, rash, and flushing. When administered intravenously, it should be given slowly, or it may cause hypotension, especially for patients with hypertension. Long-term and large-dose use can lead to bleeding tendency. Patients with hypotension should use it with caution, and it is contraindicated for patients with hypotension due to myocardial infarction. The use of this drug in the treatment of ischemic cardiomyopathy may lead to "coronary artery steal" and worsen symptoms.