Which medications are categorized as immunosuppressants?

Immunosuppressive drugs include glucocorticoids, calcineurin inhibitors, antiproliferative and antimetabolic drugs, and antibody-based drugs. These drugs can not only effectively inhibit the immune response of the body, but also interfere with normal immune response. In other words, immunosuppressive drugs are non-selective and non-specific, and must be guided by professional doctors when using them. Commonly used immunosuppressive drugs are:

Commonly used drugs include prednisone, prednisolone, medrol, etc.

Such as cyclosporine and tacrolimus, which are currently the most effective immunosuppressive drugs clinically. These drugs inhibit the activity of calcineurin and the dephosphorylation of t-cell nuclear factors, preventing them from entering the nucleus, inhibiting the transcription of related factors, and preventing somatic cells from responding to specific antigens.

Commonly used drugs include mycophenolate mofetil (CellCept, Myfortic, Myferic), purine analogs (azathioprine, mizoribine).

Such as basiliximab, lymphocyte globulin, etc.

The topic of drug combination is too professional and demanding, and Dr. Wang feels it difficult to explain it within a thousand words. So let's just talk about a simple and easy-to-remember basic principle: Among the above four types of drugs, you can only choose one from each type at most!