"Does the Qingkailing Injections Instruction Manual Clearly State the Dosage?"
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Source: Network
Introduction to Qingkailing Injection
There are various medications that possess the function of clearing heat and detoxifying the body. Individuals with low immunity are prone to bacterial and viral infections. Qingkailing Injection is one such commonly used medication, but it is administered through injection and requires dilution based on the patient's condition before use. It should be used with caution by those with allergic constitutions or weak spleens and stomachs, as improper usage can lead to adverse reactions, significantly harming the patient's health. Patients should avoid self-medication without proper guidance.Dosage and Administration Specified in the Instruction
Qingkailing Injection is administered intramuscularly, with a dosage of 2-4 milliliters per day for general cases. For severe patients, it is administered intravenously at a dosage of 20-40 milliliters per day, diluted in either 200 milliliters of 10% glucose injection or 100 milliliters of sodium chloride injection. Caution should be exercised in patients with exterior syndromes manifesting as aversion to cold and fever, those with a history of drug allergies, and those with weak spleens and stomachs. Before administration, it is crucial to inquire about the patient's allergic constitution, history of drug allergies, and prior usage of Qingkailing preparations.Ingredients and Indications
The ingredients of Qingkailing Injection include bile acid, margarita (powder), hyodeoxycholic acid, gardenia fruit, buffalo horn (powder), indigo naturalis, baicalin, and honeysuckle flower. Its primary indications are for clearing heat and detoxifying, resolving phlegm and unblocking meridians, and arousing consciousness. It is used in conditions such as febrile diseases with unconsciousness, stroke with hemiplegia and disorientation, as well as acute and chronic hepatitis, hepatitis B, upper respiratory infections, pneumonia, high fever, and cerebral thrombosis or cerebral hemorrhage with the above-mentioned symptoms.Understanding Hepatitis
Hepatitis is a general term referring to inflammation of the liver, often caused by various factors such as viruses, bacteria, parasites, chemical toxins, medications, alcohol, and autoimmune disorders. These factors damage liver cells, impair liver function, and lead to a range of uncomfortable symptoms and abnormal liver function indicators.Adverse Reactions and Precautions
Occasionally, Qingkailing Injection may cause allergic reactions, manifested as rashes, facial redness, and local pain. Precautions include:- Caution in patients with exterior syndromes manifesting as aversion to cold and fever, and those with a history of drug allergies.
- Immediate discontinuation and desensitization if allergic reactions occur.
- Do not use if the solution becomes precipitated or cloudy, even after dilution with 10% glucose or sodium chloride injection.
- Avoid concurrent use with drugs such as gentamicin sulfate, penicillin G potassium, epinephrine, phenylephrine, erythromycin lactobionate, dopamine, lobeline hydrochloride, and mephentermine sulfate.
- Use the diluted injection within 4 hours.
- Control the infusion rate, with 20-40 drops/minute for children and 40-60 drops/minute for adults.
- If necessary to administer incompatible drugs, replace the infusion solution and set immediately to prevent mixed reactions in the bloodstream.
Pharmacological Effects
Qingkailing Injection exhibits the following pharmacological effects:- Antipyretic effect, inhibiting bacterial endotoxin and endogenous pyrogen-induced fever in rabbits.
- Protective effect on brain tissue, prolonging survival and post-stroke survival time in susceptible spontaneously hypertensive rats, promoting the absorption of cerebral hemorrhage foci, and improving blood gas abnormalities in rabbits with autohematic hematoma-induced cerebral hematoma.
- Anti-hepatic injury effect, reducing hepatocyte degeneration and necrosis in rats with carbon tetrachloride-induced liver injury, increasing RNA and protein content in hepatocytes, and enhancing the activity of redox enzymes on hepatocyte mitochondria.
