What is the Normal Range for Serum Transferrin?

Update Date: Source: Network

Iron is an essential trace element for our bodies, and during physical examinations, we can conduct a serum transferrin test to check if it is normal. Therefore, it is helpful to have a basic understanding of the normal range of serum transferrin, which can assist us in making judgments during physical examinations. If any abnormalities are detected, we can promptly consult a doctor. What is the normal range of serum transferrin?

The normal range of serum transferrin may vary slightly among different hospitals and laboratories, but it generally falls within the range of 28.6 to 51.9. If transferrin levels are found to be low, it is necessary to investigate if this could be due to anemia.

The clinical significance of serum iron testing includes:

(1) Pathological elevation:

1. Increased erythrocyte destruction, such as hemolytic anemia.

2. Disorders in erythrocyte regeneration or maturation, such as aplastic anemia and megaloblastic anemia.

3. Decreased iron utilization, such as hematopoietic dysfunction caused by lead poisoning or vitamin B6 deficiency.

4. Increased release of stored iron, such as acute hepatocyte damage and necrotic hepatitis.

5. Increased iron absorption, such as hemochromatosis and hemosiderosis.

6. Acute toxicity caused by repeated blood transfusions or intramuscular injection of iron preparations.

(2) Pathological reduction:

1. Insufficient iron intake, such as malnutrition, gastrointestinal disorders, peptic ulcer, and chronic diarrhea.

2. Increased iron loss, such as blood loss (both massive and occult), especially in cases of nephritis, renal tuberculosis, vaginal bleeding, and ulcerative diseases, as well as bleeding in the urogenital tract and gastrointestinal tract.

3. Increased iron demand without timely supplementation, such as during pregnancy and infant growth.

4. Decreased release of stored iron, such as in acute and chronic infections and uremia.

5. Certain drug treatments, such as adrenocorticotropic hormone or adrenocortical hormones, high doses of aspirin, and colestipol.

(3) Physiological reduction:

During menstruation, pregnancy, and infancy, the need for iron increases, leading to a decrease in serum iron levels. This is a physiological phenomenon.