What Are the Key Differences Between Gastric Ulcer and Ulcerative Gastric Cancer?

Gastric ulcer and ulcerative gastric cancer are two distinct diseases, but they are easily confused due to their similar symptoms. In fact, there are many differences between gastric ulcer and ulcerative gastric cancer in many aspects. It is important to distinguish between these diseases in order to effectively address and treat them. The differences between gastric ulcer and ulcerative gastric cancer are also reflected in symptoms and disease nature.

1. Age difference: Gastric ulcer is more common in young and middle-aged adults. Ninety percent of patients experience epigastric pain, which occurs periodically and can last for days, weeks, or even months. The pain is relieved for a certain period of time before recurring again, often lasting for many years. In contrast, gastric cancer is more common in individuals over 40 years old. Early gastric cancer usually does not cause significant discomfort, but once symptoms such as epigastric pain appear, they progress rapidly and the course of the disease is short.

2. Difference in diet: Patients with gastric ulcer generally have good overall condition, good appetite, and respond well to drug treatment. Anemia is rare, and there is no enlargement of systemic lymph nodes. In contrast, gastric cancer patients often have poor appetite, and in the late stages, they may lose their appetite completely and become progressively emaciated. Anemia is common, and enlarged lymph nodes can be felt on the left clavicle, and sometimes a mass can be palpated in the epigastrium.

3. Difference in pain regularity: The pain associated with gastric ulcer is closely related to diet, usually starting half an hour after meals and lasting for several hours with a burning sensation. The pain gradually disappears until the next meal, when the same pattern is observed again. Pain relief can be achieved with alkaline medication. In contrast, the pain associated with gastric cancer is irregular and not related to eating. The pain may worsen or improve after eating, and the nature of the pain varies, ranging from dull to severe, often accompanied by a sense of fullness. In the late stages, the pain becomes more severe and persistent, and cannot be relieved even with alkaline medication.