"What Steps Should I Take When Experiencing Discomfort Following Discontinuation of Dailixin?"

Update Date: Source: Network

Stopping Deanxit and Managing Potential Discomfort

Due to escalating mental pressures, individuals may encounter anxiety, culminating in depression, a daunting prospect. Prompt treatment is crucial to avert suicidal ideation. Among therapeutic interventions, medication, including Deanxit, plays a role. However, prolonged medication use is discouraged. Upon improvement, dosage tapering is advised, avoiding abrupt cessation to prevent adverse symptoms. Vigilance is paramount in this regard.

If Deanxit discontinuation elicits discomfort, two scenarios may arise: either anxiety and depression symptoms persist, necessitating dosage reinstatement; or psychological dependence manifests, as Deanxit seldom induces physical addiction. Addressing the latter, relaxation, distraction through hobbies like singing, dancing, yoga, or qigong, can alleviate symptoms within days.

Deanxit cessation should be gradual, e.g., reducing the initial dosage by a third, followed by another reduction after two weeks, contingent on tolerability. For patients struggling with medication tapering, crushing tablets and administering 1ml of the mixture in 100ml water each time can facilitate the process.

Reactions Following Deanxit Discontinuation

International studies affirm Deanxit's minimal side effects within therapeutic doses, typically mild and transient, resolving within 1-2 weeks. Potential side effects encompass dry mouth and sleep disturbances with nighttime dosing. Rare adverse reactions may include transient anxiety and insomnia.

Clinical trials have documented neurological reactions like dizziness (2.1%) and tremor (2.1%), fatigue (1%), psychiatric reactions such as sleep disorders (6%), anxiety (2.5%), agitation (1.7%), visual dysfunction (1.5%), and gastrointestinal discomfort including dry mouth (5.4%) and constipation (1.5%). These reactions may overlap with depression symptoms, potentially obscuring therapeutic gains.

Physician-guided Deanxit cessation is recommended to assess patient status and mitigate adverse events. For patients managing discomfort unrelated to Deanxit's therapeutic indications, self-administered cessation may be feasible due to the medication's benign post-cessation profile.

Deanxit's Efficacy and Composition

Deanxit's active ingredients are flupentixol and melitracen, formulated as flupentixol and melitracen tablets. Flupentixol, a neuroleptic, addresses neurosis, gastrointestinal neurosis, senile depression, menopausal syndrome, and related conditions. It effectively alleviates depressive and anxious sentiments, somatic symptoms, neurosis, neurasthenia, and autonomic nervous dysfunction, exhibiting analgesic and anticonvulsant properties without antipsychotic effects.

Deanxit's decade-long international usage and seven-year Chinese adoption have benefited over 110 million individuals, demonstrating efficacy in treating neurosis, anxiety, and depression associated with various physical ailments.

Deanxit Elimination Dynamics

Deanxit's flupentixol and melitracen combination preserves their individual pharmacokinetic profiles. Post-oral administration, both components swiftly absorb, peaking in plasma within 4 hours. Flupentixol's biological half-life is approximately 35 hours, with 60% excreted fecally and 15-20% renally post-hepatic metabolism. Melitracen's half-life is roughly 19 hours, primarily excreted renally, with minimal placental and breast excretion for both components.