What Are the Effects and Benefits of Moclobemide?

Modern people face immense work and life pressures, leading to depression becoming a highly prevalent mental illness. Minor depression can manifest in symptoms such as negativity, anxiety, and loneliness, while severe depression can even result in suicidal thoughts. Moclobemide is a medication used to treat depression and can exert an antidepressant effect. After discovering symptoms of depression, it is essential to follow the doctor's instructions for medication and maintain a pleasant mood to truly overcome depression.

The Role of Moclobemide

Moclobemide is a monoamine oxidase inhibitor antidepressant. Its mechanism of action involves reversibly inhibiting type A monoamine oxidase in the brain, thereby increasing the levels of norepinephrine, dopamine, and serotonin in the brain to exert an antidepressant effect. It acts quickly, and monoamine oxidase activity recovers rapidly after discontinuation.

Dosage of Moclobemide

1. The general daily dosage is 300mg, which can be adjusted to 150mg or 600mg daily depending on the severity of the condition, taken after meals.

2. For the elderly or patients with liver dysfunction, dosage adjustment is not required; however, patients with severe liver dysfunction should reduce the dosage by 1/3 to 1/2.

Adverse Reactions of Moclobemide

1. Mild nausea, dry mouth, headache, dizziness, excessive sweating, palpitations, insomnia, orthostatic hypotension, etc.

2. Allergic skin reactions are rare.

3. Occasional cases of consciousness impairment, elevated blood pressure, liver function impairment, etc.

4. High doses can induce seizures.

How to Cope with Depression

Learn to regulate your emotions, avoid being overwhelmed by stress, balance work and rest, exercise appropriately, and relax your mind. You can also travel more, enjoy the scenery, and adjust your mood. Depression is similar to laziness and can be easily overlooked. Once such symptoms appear, it is important to adjust promptly to avoid depression.