Could a Child Have Type A Blood If Both Parents Have Type O?
The most common blood types are ABO. Our blood type is influenced by genetic factors. With the knowledge of our parents' blood types and the laws of inheritance, we can roughly predict our own blood type and exclude those that are impossible. However, many people do not have a good understanding of genetic laws, which can lead to various doubts. For example, if both parents have O-type blood, what blood type will their child have? Could it be A-type? Let's take a look at this issue.
Firstly, the ABO blood type is controlled by three genetic genes: A, B, and O. However, there are only two ABO system genetic genes on the 9th pair of sex chromosomes in each tissue cell, namely one of the allelic genes in AO, AA, BO, BB, AB, and OO. Among them, A and B are dominant genes, while O is a recessive gene. If both parents have O-type blood, their child will only have one blood type, which is O-type. O-type blood does not have A antigen or B antigen, but it will have anti-A and anti-B agglutinins in the blood cells. Under normal conditions, their child is likely to have O-type blood, which is determined by the regularity of ABO blood type inheritance. The ABO blood type system is the most common blood type system in clinical medicine, which is inheritable, and the blood type remains unchanged throughout life.
However, there is an exception. If the mother of the child has the Bombay blood type, the child could possibly have A-type blood. The Bombay blood type is actually a rare blood type, also known as pseudo-O blood type. It is a very rare blood type that lacks A, B, and H antigens on the blood cells, but has A, B, and anti-H antigens present in the blood cells.
Secondly, blood type is generally unchanged throughout life. Human blood types are usually classified into four types: A, B, O, and AB. Blood type inheritance is mediated by chromosomes in cells. Human cells contain 23 pairs of chromosomes, each pair consisting of two single chromosomes, one from the father and one from the mother. The main component of chromosomes is deoxyribonucleic acid (DNA), which determines genetic traits and functions. DNA can be divided into many small segments, each with a specific genetic trait and function, known as genes. The DNA segments at the same position on the two single chromosomes in a pair of chromosomes are called allelic genes. The gene loci of the ABO blood type system are located on the 9th pair of chromosomes.
Human ABO blood type is controlled by three genes: A, B, and O. However, there are only two ABO system genes on the 9th pair of chromosomes in each human cell, namely one of the allelic genes in AO, AA, BO, BB, AB, and OO. Among them, A and B genes are dominant genes, while O gene is a recessive gene.
