"What are the best medications for treating knee pain?"

It is important to clarify that there is no absolutely best medication for treating knee pain, and the choice of medication depends on the specific cause and degree of the pain. The following medications may be considered, including non-steroidal anti-inflammatory drugs (NSAIDs), analgesics, chondroprotective agents, immunosuppressants and antirheumatic drugs, uric acid-lowering drugs, among others.

1. Non-Steroidal Anti-Inflammatory Drugs (NSAIDs):

Examples include Ibuprofen Sustained Release Capsules and Naproxen Tablets. These have anti-inflammatory, analgesic, and antipyretic effects, which can alleviate mild to moderate knee pain. Long-term use may increase the risk of gastrointestinal ulcers and bleeding, hence adherence to instructions is crucial.

2. Analgesics:

Such as Paracetamol Tablets and Tramadol Hydrochloride Tablets. These are primarily used for pain relief and can be effective for knee pain. However, analgesics do not eliminate inflammation, and excessive use may lead to side effects like nausea and vomiting.

3. Chondroprotective Agents:

For instance, Glucosamine Hydrochloride and Chondroitin Sulfate. They are used for knee pain caused by cartilage damage, such as in osteoarthritis, by repairing joint cartilage and reducing pain. Long-term use is necessary, and the effects may vary among individuals.

4. Immunosuppressants and Antirheumatic Drugs:

Examples are Prednisone Tablets and Methotrexate Tablets. These are primarily used to treat knee pain caused by diseases like rheumatoid arthritis, with immunosuppressive and anti-inflammatory effects. They have significant side effects and should be used under medical supervision with monitoring of liver and kidney function.

5. Uric Acid-Lowering Drugs:

Such as Probenecid Tablets and Benzbromarone Tablets. These are used for knee pain caused by gouty arthritis, by lowering uric acid levels and reducing pain. Dosage adjustment is required based on uric acid levels to avoid gout flares.

The above medications are common choices, but specific usage should be determined by medical advice and individual circumstances. Additionally, the treatment of knee pain encompasses not only medications but also physical therapy, rehabilitation training, and other methods. A personalized treatment plan should be devised considering the patient's specific situation.