The statement that saffron should be stopped every three days is unscientific. Generally, it is not recommended to consume saffron for a long period without a break every three days. Saffron has certain toxicity and can irritate the gastrointestinal mucosa. Excessive consumption of saffron may lead to acute gastroenteritis, dyspepsia, and other gastrointestinal diseases. Therefore, it is not necessary to stop consuming saffron every three days; the key is to control the dosage. Saffron is generally consumed 3 to 4 times a week. It is recommended to steep saffron in water once every other day, which means steeping it 3 to 4 times a week, rather than following the rule of stopping every three days. It is also unnecessary to consume it every day, as it may adversely affect the body. Daily consumption may prolong the menstrual period and increase menstrual blood flow in women, leading to anemia. Additionally, pregnant women should avoid consuming saffron as it may irritate the uterus, cause uterine excitement, stimulate neurological disorders, and potentially lead to miscarriage. In summary, the statement that saffron should be stopped every three days is not absolute. Generally, it is advisable to consume saffron in moderation as prescribed by a doctor. Before consuming saffron, to avoid adverse reactions, it is recommended to consult a doctor for advice.