What Are the Side Effects of Yisaipu?

The full name of Yisaipu is recombinant human type II tumor necrosis factor receptor-antibody fusion protein for injection. Common adverse reactions are local reactions at the injection site, including mild to moderate erythema, itching, pain, swelling, etc. Recombinant human type II tumor necrosis factor receptor-antibody fusion protein for injection is used to treat moderate to severe active rheumatoid arthritis; moderate to severe plaque psoriasis in adults aged 18 and over; active ankylosing spondylitis. Reactions at the injection site usually occur within the first month of starting treatment, and the frequency decreases during subsequent treatments. The average duration of injection site reactions is 3-5 days. Other adverse reactions include headache, dizziness, rash, insomnia, cough, abdominal pain, upper respiratory infection, increased blood pressure, increased peripheral blood lymphocyte ratio, rhinitis, fever, joint soreness, muscle soreness, drowsiness, facial swelling, elevated transaminase, etc. Most of them do not require treatment. Therefore, patients with a history of recurrent infections or latent diseases that can lead to infections should be extremely cautious when using this product. If patients develop repeated upper respiratory infections or other obvious signs of infection during the use of this product, they should seek medical attention promptly and receive guidance from a doctor for treatment based on specific conditions. When serious infections such as diabetes-related infections, Mycobacterium tuberculosis infections, etc., occur, patients should discontinue the use of this product. During the use of this product, attention should be paid to the occurrence of allergic reactions, including angioedema, urticaria, and other severe reactions. Therefore, once an allergic reaction occurs, the treatment with this product should be immediately discontinued and appropriate measures should be taken.